Biology and Biotechnology: Recent submissions
Now showing items 161-180 of 193
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Interaction of haptoglobin with hemoglobin octamers based on the mutation αAsn78Cys or βGly83Cys
(Scientific Research Publishing, 2012-01)Octameric hemoglobins have been developed by the introduction of surface cysteines in either the alpha or beta chain. Originally designed as a blood substitute, we report here the structure and ligand binding function; in ... -
HPV positivity varies with technique and primer set, in formalin-fixed paraffin-embedded benign and malignant breast tissue from Malta
(Scientific Research Publishing, 2011-10)The role of human papillomavirus in breast cancer pathogenesis is an area of considerable debate following differing results from all over the world. This study analyzed paraffin embedded tissue from 19 patients with benign ... -
Codon bias of influenza a viruses and their hosts
(Scientific Research Publishing, 2011-10)The Influenza A virus remains an annual and worldwide health concern due to its fast evolutionary rate. There are two major forms of Influenza evolution: drift, caused by mutations, and shift, which results from the exchange ... -
An investigation of 10 Y-STR loci and the detection of specific haplotype frequencies in Turkish population
(Scientific Research Publishing, 2011-07)This study is to survey 10 Y-STR loci in 241 males from Turkey. In this study, the 241 healthy and unrelated males living in different parts of Turkey for at least three generations were included. Genomic DNAs were isolated ... -
Effects of genetic and environmental factors and gene-environment interaction on expression variations of genes related to stroke in rat brain
(Scientific Research Publishing, 2011-07)To determine if genetic and environmental (dietary) factors and gene-environment interaction impact on the expression variation of genes related to stroke, we conducted microarray experiments using two homozygous rat strains ... -
A reduced computational load protein coding predictor using equivalent amino acid sequence of DNA string with period-3 based time and frequency domain analysis
(Scientific Research Publishing, 2011-07)Development of efficient gene prediction algorithms is one of the fundamental efforts in gene prediction study in the area of genomics. In genomic signal processing the basic step of the identification of protein coding ... -
N–nitrosodiethylamine cytochrome P450 induction and cytotoxicity evaluation in primary cultures of rat hepatocytes
(Scientific Research Publishing, 2011-07)The primary routes of potential human exposure to N-nitrosodiethylamine (NDEA) are ingestion, inhalation, and dermal contact. Air, diet and smoking contribute to potential human exposure at levels of a few µg of NDEA/day. ... -
Influence OF anticancer drugs on DNA methylation in liver of female mice
(Scientific Research Publishing, 2011-06)Epigenetic changes such as DNA methylation regulate gene expression in normal development. Methotrexate and Adriamycine are antineoplastic drugs that target DNA and enzymes acting on DNA. We aimed to evaluate their cytotoxic ... -
Characterization of asian and north American avian H5N1
(Scientific Research Publishing, 2011-07)Since the emerge of the highly pathogenic avian H5N1 virus in Asia in 1996, the possibility for this virus to cross species barriers to infect humans and its ability to cause large outbreaks in birds have been a public ... -
Gene expression profiling in soybean under aluminum stress: genes differentially expressed between Al-tolerant and Al-sensitive genotypes
(Scientific Research Publishing, 2011-10)It is well documented that aluminum (Al) toxicity is the most important constraint to crop production on acid soils and soybean is one of the most Al sensitive plant species. To advance our understanding of the molecular ... -
JnCML-like, an EF-hand motif-containing gene seasonally upregulated in the transition zone of black walnut (Juglans nigra L.)
(Scientific Research Publishing, 2011-10)The economic value of a black walnut (Juglans nigra L.) tree is strongly determined by the quality and quantity of darkly colored heartwood in its stem. To understand the regulation of heartwood formation, we analyzed the ... -
EGR1 is essential for transcriptional regulation of BMPR2
(Scientific Research Publishing, 2011-10)In this study, RLM-RACE was used to identify the transcriptional start site 387 bp upstream of the translational start. Evolutionarily conserved transcription factor binding sites were identified, and a series of luciferase ... -
Cytosolic chaperonin CCT possesses GTPase activity
(Scientific Research Publishing, 2011-10)Cytosolic chaperonin CCT (also known as TRiC) is a hetero-oligomeric cage-like molecular chaperone that assists in protein folding by ATPase cycle-dependent conformational changes. However, role of the nucleo-tide binding ... -
Unusual metallo-β-lactamases may constitute a new subgroup in this family of enzymes
(Scientific Research Publishing, 2014-01)Metallo-β-lactamases (MBLs) are a family of Zn2+-dependent enzymes that have contributed strongly to the emergence and spread of antibiotic resistance. Novel members as well as variants of existing members of this family ... -
A method to synthesize cDNA constructs by homology based recombination cloning
(Scientific Research Publishing, 2014-01)We introduce a homology-based recombination approach for generating a cDNA construct. This method depends on amplifying several exon fragments and their fusions by the homology-based recombination. This method provides a ... -
Polysaccharides as initiators of nucleic acid polymerization
(Scientific Research Publishing, 2014-10)Quantum-chemical calculations and in vitro experiments have demonstrated that polysaccharides are able to adsorb mononucleotides due to the formation of hydrogen bonds. The subsequent dehydration of polysaccharide-nucleotide ... -
Super-Enhancement and Control of Amh Expression
(Scientific Research Publishing, 2016-07)In previous work it was shown that mutation of site 1 in the downstream enhancer sequence (DE) led to ablation of enhancement. Mutation of the Wilms tumour factor element (Wt), situated in the Amh promoter between the tata ... -
Expression Analysis of WRKY Transcription Factor Genes in Response to Abiotic Stresses in Horsegram (Macrotyloma uniflorum (Lam.) Verdc.)
(Scientific Research Publishing, 2016-10)Drought and salt stress are two major environmental constraints that limit the productivity of agriculture crops worldwide. WRKY transcription factors are the plant-specific transcription factors that regulate several ... -
The Potential of DNA Barcode-Based Delineation Using Seven Putative Candidate Loci of the Plastid Region in Inferring Molecular Diversity of Cowpea at Sub-Species Level
(Scientific Research Publishing, 2016-10)The novelty and suitability of the mitochondrial gene CO1 in DNA barcoding as a reliable identification tool in animal species are undisputed. This is attributed to its standardized sequencing segment of the mitochondrial ... -
Ghrelin-induced cSrc activation through constitutive nitric oxide synthase-dependent S-nitrosylation in modulation of salivary gland acinar cell inflammatory responses to Porphyromonas gingivalis
(Scientific Research Publishing, 2011-07)A peptide hormone, ghrelin, recognized for its role in the regulation of nitric oxide production has emerged as an important modulator of oral mucosal inflammatory responses to periodontopathic bacterium, P. gingivalis. ...
