Browsing Biology and Biotechnology by Title
Now showing items 120-139 of 193
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Interaction between the Wilms tumour factor-1 element in the promoter of Amh and a downstream enhancer is required for a strong expression of the gene in pre-pubertal sertoli cells
(Scientific Research Publishing, 2013-07)Amh (anti-Müllerian hormone) is a single copy gene which is expressed strongly in Sertoli cells in the foetal testis and participates in the onset of sexual differentiation. Its promoter driving the expression of a reporter ... -
Interaction of haptoglobin with hemoglobin octamers based on the mutation αAsn78Cys or βGly83Cys
(Scientific Research Publishing, 2012-01)Octameric hemoglobins have been developed by the introduction of surface cysteines in either the alpha or beta chain. Originally designed as a blood substitute, we report here the structure and ligand binding function; in ... -
Intergenic subset organization within a set of geographically-defined viral sequences from the 2009 H1N1 influenza A pandemic
(Scientific Research Publishing, 2012-01)We report a bioinformatic analysis of the datasets of sequences of all ten genes from the 2009 H1N1 influenza A pandemic in the state of Wisconsin. The gene with the greatest summed information entropy was found to be the ... -
Investigating genotoxicity of Eleusine indica by micronuclei assay in albino rats
(African Journal of Biological Sciences, 2019-01-16)Genotoxicity of Eleusine indica (Nkim enang: Efik) was investigated in the Wister strain albino rat (Rattus novergicus). Nine (9) male and nine (9) female rats were randomly assigned to three (3) groups, of which two were ... -
An investigation of 10 Y-STR loci and the detection of specific haplotype frequencies in Turkish population
(Scientific Research Publishing, 2011-07)This study is to survey 10 Y-STR loci in 241 males from Turkey. In this study, the 241 healthy and unrelated males living in different parts of Turkey for at least three generations were included. Genomic DNAs were isolated ... -
JnCML-like, an EF-hand motif-containing gene seasonally upregulated in the transition zone of black walnut (Juglans nigra L.)
(Scientific Research Publishing, 2011-10)The economic value of a black walnut (Juglans nigra L.) tree is strongly determined by the quality and quantity of darkly colored heartwood in its stem. To understand the regulation of heartwood formation, we analyzed the ... -
Knockdown of Dock7 in vivo specifically affects myelination by Schwann cells and increases myelin thickness in sciatic nerves without affecting axon thickness
(Scientific Research Publishing, 2012-07)During development of the peripheral nervous system (PNS), Schwann cells (SCs) wrap individual axons to form myelin sheaths, which act as surrounding insulators and markedly enhance the propagation of the action potential. ... -
Malaria vectors distribution, abundance and assessment of factors influencing acceptance and use of Insecticide Treated Nets in Uyo Akwa Ibom State Nigeria
(African Science Publications, 2021-01-01)The abundance and distribution of malaria vectors as well as compliance with the use of Insecticide Treated Nets (ITNs) are key factors in the fight against malaria. Malaria vector species composition, distribution and ... -
Marek’s disease virus challenge induced immune-related gene expression and chicken repeat 1 (CR1) methylation alterations in chickens
(Scientific Research Publishing, 2012-07)Marek’s disease virus (MDV) challenge induces lymphoma in susceptible chickens. Host genes, especially immune related genes, are activated by the virus. DNA methylation is an epigenetic mechanism that governs gene ... -
Mechanisms of biochar and vermicompost in suppression of root rot fungal disease of common bean (Phaseolus vulgaris L)
(African Science Publications, 2021-04-05)Composts and biochar improve soil fertility and also suppress fungal soil-borne diseases through their ability to promote beneficial microbial communities. The study sought to determine the mechanisms through which biochar ... -
The mechanisms of virulence and antimicrobial resistance in Salmonella enterica serovar Typhi: A systematic review
(African Science Publications, 2020-10-05)Salmonella enterica serovar Typhi is the etiologic agent of typhoid fever which is responsible for about 21,600 deaths annually, a large proportion of which is reported in developing countries. The organism is capable of ... -
A method to synthesize cDNA constructs by homology based recombination cloning
(Scientific Research Publishing, 2014-01)We introduce a homology-based recombination approach for generating a cDNA construct. This method depends on amplifying several exon fragments and their fusions by the homology-based recombination. This method provides a ... -
Modulation of gastric mucosal inflammatory responses to Helicobacter pylori by ghrelin: Role of cNOS-dependent IKK-β S-nitrosylation in the regulation of COX-2 activation
(Scientific Research Publishing, 2012-04)Disturbances in nitric oxide synthase (NOS) and cyclooxygenase (COX) isozyme systems, manifested by the excessive NO and prostaglandin (PGE2) generation, are well-recognized features of gastric mucosal inflammatory responses ... -
Molecular characterization and species composition of anopheline vectors of malaria along an altitudinal gradient on the highlands of Mambilla Plateau Northeast, Nigeria
(African Journal of Biological Sciences, 2020-01-01)Diversity of species arises majorly from speciation and this has serious epidemiological implications to disease transmission. The study aimed to determine the species of anopheline vectors of malaria present in five ... -
Molecular cloning and characterization of fruit specific promoter from Cucumis sativus L.
(Scientific Research Publishing, 2012-04)The isolation and characterization of fruit specific promoters are critical for the manipulation of nutritional value and agronomic quality of fruits by genetic engineering and also opened a new era in edible vaccine ... -
Molecular docking investigation for Indonesian H274Y mutant neuraminidase type 1 with neuraminidase inhibitors
(Scientific Research Publishing, 2012-01)The aim of this study is to get insight the interaction between Indonesian H274Y mutant neuraminidase with four inhibitors. Not only to seek preferable inhibitor to be used, but also to investigate the interaction occurred, ... -
Molecular identification of endophytic fungi associated with orchids from Mount Cameroon region
(African Science Publications, 2021-04-05)The orchidaceae (orchid family) is the second largest family of flowering plants after the Asteraceae. Orchids are important in herbal medicine, the food industry, perfumery industry and as ornamentals. They rely on ... -
The molecular regulatory effect of intracerebroventricular thymulin on endotoxin-mediated NF-kB nuclear translocation and activation in vivo
(Scientific Research Publishing, 2013-01)The nuclear factor-kB (NF-kB) is one member of a ubiquitously expressed family of Rel-related transcription factors that serve as critical regulators of proinflammatory genes. The immunomodulatory potential of thymulin and ... -
Molecular surveillance of dengue virus in Bahia State, Brazil
(Scientific Research Publishing, 2012-01)Dengue is an important emerging viruses, posing a threat to one-third of the global human population. In 2002, the introduction of DENV-3 in the state of Bahia produced massive epidemic (about 35,000 cases detected) and ... -
A multi-criteria decision-making approach for comparing sample preservation and DNA extraction methods from swine feces
(Scientific Research Publishing, 2012-04)Molecular microbiological methods, such as competetive PCR, real-time PCR, denaturing gradient gel electrophoresis (DGGE) and large-scale parallel-pyrosequencing, require the extraction of sufficient quantity of high quality ...