Browsing by Author "Wanyonyi, Alphonse W."

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    Bioactive steroidal alkaloid glycosides from Selanum aculeastrum.
    (2002) Wanyonyi, Alphonse W.; Chhabra, S.C.; Mkoji, G.; Eilert, Udo; Njue, Wilson N.
    Solanum aculeastrum Dunal was investigated for the presence of molluscicidal compounds. This led to the isolation of solaculine A, from the root bark in addition to known steroidal alkaloids; solamargine and beta-solamarine from the berries. The structures were elucidated by spectroscopic techniques. Molluscicidal activity of the aqueous extracts of the berries and root bark, and the isolated compounds were investigated.
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    molluscicidal and antimicrobial activity of solanum aculeastrum
    (2003) Wanyonyi, Alphonse W.; Chhabra, S.C.; Mkojo, G.; Njue, Wilson N.; Tarus, Paul K.
    The methanolic extract of the fresh root bark and berries of Solanum aculeastrum showed significant activity against host snails of schistosomiasis. The berries extract was more potent with 100% snail kill at 50 ppm. Fractionation increased activity with 100% mortality at 20 ppm. The aqueous and methanolic extracts of the berries showed moderate antimicrobial activity, increasing by fractionation.