Browsing by Author "Anigbo, E.U."

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    The diagnostic value of haematuria and proteinuria in Schistosoma haematobium infection in Southern Nigeria.
    (1992) Nwaorgu, O.C.; Anigbo, E.U.
    Haematuria and proteinuria as detected by chemical reagent strips correlated moderately (r=0·7) with prevalence and intensity of infection with Schistosoma haematobium in an area of Anambra State, Nigeria. Differences attributable to age and sex were also reflected in a similar pattern, all peaks occurring in the 5–14 year age group. The differences observed with varying levels of intensity and haematuria at both 10 and 50 erythrocytes/μl (p<0·001) and proteinuria at 0·3 g/dl (p<0·01) were statistically significant. At a proteinuria level of 1 g/dl, the observed differences were however not statistically significant (p>0·5). The percentage of specimens from children (1–14 years) positive for S. haematobium eggs and with at least traces of haematuria and proteinuria (63·4% and 95%, respectively) was higher than in adults (33·3% and 80·2%, respectively). All individuals with more than 50 eggs/10 ml of urine were correctly identified using both indices either separately or in combination. For egg counts of less than 50 egg/10 ml of urine, false diagnosis occurred in only 5% of all specimens examined. The sensitivity and specificity of haematuria and proteinuria at trace quantities was very high, hut haematuria had a higher predictive value for a positive test (PvPt) and was considered the overall better indicator. A combination of both indices did not significantly increase the PvPt. When trace haematuria and moderate proteinuria were combined, both the sensitivity, specificity and PvPt were all above 90%, giving the best overall values in all the combinations made.
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    Urinary Schistosomiasis in two family populations, using school children as tracers
    (1988) Anigbo, E.U.; Nwaorgu, O.C.
    Two groups of families designated A and B were studied for Schistosoma haematobium infection in Amagunze, Anambra State, Nigeria. The groups were selected on the basis of a preliminary screening of schoolchildren: group A were children with negative urine samples and group B were those with positive samples. Each group contained 60 children and the families of each of these were screened for schistosomiasis. The total prevalence among the 1017 individuals examined was 48.4% and the mean egg count was 72/10 ml urine. The peak prevalence (73%) and intensity of infection (84 eggs/10 ml of urine) occurred between the ages of 5 and 14 years. The prevalence and intensity of S. haematobium infection was statistically higher in males than in females. Although water contact patterns were similar, families in group B were significantly more infected (59%) than those in group A (36%).