Browsing Biology and Biotechnology by Issue Date
Now showing items 21-40 of 193
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Intergenic subset organization within a set of geographically-defined viral sequences from the 2009 H1N1 influenza A pandemic
(Scientific Research Publishing, 2012-01)We report a bioinformatic analysis of the datasets of sequences of all ten genes from the 2009 H1N1 influenza A pandemic in the state of Wisconsin. The gene with the greatest summed information entropy was found to be the ... -
Interaction of haptoglobin with hemoglobin octamers based on the mutation αAsn78Cys or βGly83Cys
(Scientific Research Publishing, 2012-01)Octameric hemoglobins have been developed by the introduction of surface cysteines in either the alpha or beta chain. Originally designed as a blood substitute, we report here the structure and ligand binding function; in ... -
Molecular surveillance of dengue virus in Bahia State, Brazil
(Scientific Research Publishing, 2012-01)Dengue is an important emerging viruses, posing a threat to one-third of the global human population. In 2002, the introduction of DENV-3 in the state of Bahia produced massive epidemic (about 35,000 cases detected) and ... -
Effect of hypoxia and glutamine or glucose deprivation on the expression of retinoblastoma and retinoblastoma-related genes in ERN1 knockdown glioma U87 cell line
(Scientific Research Publishing, 2012-01)The expression of retinoblastoma and several retinoblastoma-related genes was studied in glioma cell line U87 and its subline with knockdown of ERN1 (endoplasmic reticulum—nuclei-1), the main endoplasmic reticulum stress ... -
Molecular docking investigation for Indonesian H274Y mutant neuraminidase type 1 with neuraminidase inhibitors
(Scientific Research Publishing, 2012-01)The aim of this study is to get insight the interaction between Indonesian H274Y mutant neuraminidase with four inhibitors. Not only to seek preferable inhibitor to be used, but also to investigate the interaction occurred, ... -
The ATPase activity of molecular chaperone HSP60 is inhibited by immunosuppressant mizoribine
(Scientific Research Publishing, 2012-04)The molecular chaperone HSP60 is a chaperonin homolog of GroEL. We had previously shown that the immunosuppressant mizoribine is bound directly to HSP60 and inhibited its chaperone activity. However, the inhibitory mechanisms ... -
Oxidized phospholipids modify plasminogen and apolipoprotein(a): Implications for vascular disease
(Scientific Research Publishing, 2012-04)Whereas the close structural homology between human plasminogen and apolipoprotein(a) has been known for a number of years only recent studies have revealed that both proteins carry linked oxidized phospholipids that may ... -
Modulation of gastric mucosal inflammatory responses to Helicobacter pylori by ghrelin: Role of cNOS-dependent IKK-β S-nitrosylation in the regulation of COX-2 activation
(Scientific Research Publishing, 2012-04)Disturbances in nitric oxide synthase (NOS) and cyclooxygenase (COX) isozyme systems, manifested by the excessive NO and prostaglandin (PGE2) generation, are well-recognized features of gastric mucosal inflammatory responses ... -
The effects of astragalus polysaccharide on zebrafish cell apoptosis and senescence
(Scientific Research Publishing, 2012-04)Astragalus polysaccharide (AP) is the extraction of astragalus, which is a plant used in traditional Chinese herb medicine and may increase an orgainism’s resistance to stress. Several earlier studies in vitro have indicated ... -
Solving the independent set problem by sticker based DNA computers
(Scientific Research Publishing, 2012-04)In this paper, the sticker based DNA computing was used for solving the independent set problem. At first, solution space was constructed by using appropriate DNA memory complexes. We defined a new operation called “divide” ... -
A multi-criteria decision-making approach for comparing sample preservation and DNA extraction methods from swine feces
(Scientific Research Publishing, 2012-04)Molecular microbiological methods, such as competetive PCR, real-time PCR, denaturing gradient gel electrophoresis (DGGE) and large-scale parallel-pyrosequencing, require the extraction of sufficient quantity of high quality ... -
Molecular cloning and characterization of fruit specific promoter from Cucumis sativus L.
(Scientific Research Publishing, 2012-04)The isolation and characterization of fruit specific promoters are critical for the manipulation of nutritional value and agronomic quality of fruits by genetic engineering and also opened a new era in edible vaccine ... -
Expression of the transcription factor Xvent-2 in Xenopus laevis embryogenesis
(Scientific Research Publishing, 2012-04)Till now the transcription factor Xvent-2 has been studied in Xenopus embryos only by the mRNA testing. We use immunochemical methods for testing of the Xvent-2 protein and gradient-centrifugation methods for estimation ... -
Tandem repetitions in transcriptomes of some Solanaceae species
(Scientific Research Publishing, 2012-04)Characterization of occurrence, density and motif sequence of tandem repeats in the transcribed regions is helpful in understanding the functional significance of these repeats in the modern genomes. We analyzed tandem ... -
The restriction endonuclease Tru9I is a useful tool to analyze telomere sequences separately from interstitial telomeric sequences in Arabidopsis thaliana
(Scientific Research Publishing, 2012-07)We have previously described a simple method to analyze the chromatin structure of Arabidopsis telomeres independently of that of Interstitial Telomeric Sequences (ITSs). By using this method, we found that, whereas ITSs ... -
A peptide of 17 aminoacids from the N-terminal region of maize plastidial transglutaminase is essential for chloroplast targeting
(Scientific Research Publishing, 2012-07)Transglutaminases (TGases, EC 2.3.2.13) catalyse posttranslational modification of proteins by establishing ε-(γ-glutamyl) links and covalent conjugation of polyamines. In plants, the functionality of these enzymes is ... -
Expression and subcellular localization of a novel gene Bm-X of the silkworm, Bombyx mori
(Scientific Research Publishing, 2012-07)According to the large-scale sequencing of cDNA library from silkworm pupae, the cDNA of a novel gene with blank research background was identified and temporarily named Bm-X. The length of this cDNA is 778 bp. We obtained ... -
How is the biological information arranged in genome?
(Scientific Research Publishing, 2012-07)The four nucleotides (bases), A. T. G and C were sophisticatedly arranged in the structural features in a single-strand of genomic DNA, 1) reverse-complement symmetry of base or base sequences, 2) bias of four bases, 3) ... -
Identification of ebs1, lsm6 and nup159 as suppressors of spt10 effects at ADH2 in Saccharomyces cerevisiae suggests post-transcriptional defects affect mRNA synthesis
(Scientific Research Publishing, 2012-07)Suppression of the effects of an spt10 mutation on ADH2 expression is a phenotype shared by a small number of genes whose protein products are either components of the CCR4-NOT complex required for mRNA deadenylation and ... -
Knockdown of Dock7 in vivo specifically affects myelination by Schwann cells and increases myelin thickness in sciatic nerves without affecting axon thickness
(Scientific Research Publishing, 2012-07)During development of the peripheral nervous system (PNS), Schwann cells (SCs) wrap individual axons to form myelin sheaths, which act as surrounding insulators and markedly enhance the propagation of the action potential. ...