Browsing Journal Articles by Author "Zhang, Tianyu"
Now showing items 1-3 of 3
-
Advances in the development of molecular genetic tools for Mycobacterium tuberculosis
Chiranjibi, Chhotaray; Yaoju, Tan; Mugweru, Julius; Islam, Md Mahmudul; Hameed, H.M. Adnan; Wang, Shuai; Lu, Zhili; Wang, Changwei; Li, Xinjie; Tan, Shouyong; Liu, Jianxiong; Zhang, Tianyu (Elsevier, 2018-07)Mycobacterium tuberculosis, a Gram-positive bacterium of great clinical relevance, is a lethal pathogen owing to its complex physiological characteristics and development of drug resistance. Several molecular genetic ... -
Assessment of Clofazimine and TB47 Combination Activity against Mycobacterium abscessus Using a Bioluminescent Approach
Liu, Yang; Tan, Yaoju; Islam, Mahmudul M.; Cao, Yuanyuan; Lu, Xiaoyun; Zeng, Sheng; Hameed, H. M. Adnan; Zhou, Peipei; Cai, Xingshan; Wang, Shuai; Mugweru, Julius N.; Zhang, Guoliang; Yin, Huancai; Liu, Jianxiong; Nuermberger, Eric; Zhang, Tianyu (American Society for Microbiology, 2020-02)Mycobacterium abscessus is intrinsically resistant to most antimicrobial agents. The emerging infections caused by M. abscessus and the lack of effective treatment call for rapid attention. Here, we intended to construct ... -
Mutation EthAW21R confers co-resistance to prothionamide and ethionamide in both Mycobacterium bovis BCG and Mycobacterium tuberculosis H37Rv
Mugweru, Julius; Liu, Jianxiong; Makafe, Gaelle; Chiwala, Gift; Wang, Bangxing; Wang, Changwei; Li, Xinjie; Tan, Yaoju; Yew, Wing Wai; Tan, Shouyong; Zhang, Tianyu (Dove Press, 2018-06)Ethionamide (ETA) and prothionamide (PRO) are interchangeably used in tuberculosis (TB) chemotherapy regimens. Subtle discrepancies between biochemical and genetic information on the modes of sensitivity and resistance ...