Genetic variation may play a crucial role in non-coding RNA biogenesis

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dc.contributor.authorKandhavelu, Jeyalakshmi
dc.contributor.authorKandhavelu, Meenakshisundaram
dc.date.accessioned2016-10-25T06:21:59Z
dc.date.available2016-10-25T06:21:59Z
dc.date.issued2012-10
dc.description.abstractTranscription, post-transcriptional modification, translation, post-translational modification, DNA replication, and signaling interaction of intra- and extra- cellular components are the relevant mechanisms in gene regulation. Transcription is one of the most important mechanisms in the control of gene expression. Further, post-transcriptional modifications play a crucial role after transcription which determine whether the transcribed gene is coding or non-coding RNA (ncRNAs). Genome-wide analysis of RNAs provides information about the coding RNAs, whereas the status of ncRNAs are still at large and must be discussed in detail as variations in the ncRNAs can lead to different phenotypes. In this short article, we discuss the role of genetic variation in ncRNA genes and how this variation may play a crucial role in ncRNA biogenesis that eventually leads to phenotypic variation and thus speciation.en_US
dc.identifier.citationAmerican Journal of Molecular Biology, 2012, 2, 386-389en_US
dc.identifier.urihttp://dx.doi.org/10.4236/ajmb.2012.24040
dc.identifier.urihttp://hdl.handle.net/123456789/1025
dc.language.isoenen_US
dc.publisherScientific Research Publishingen_US
dc.subjectGenome Wide Analysisen_US
dc.subjectBioinformaticsen_US
dc.subjectGenetic Variationen_US
dc.subjectNon-Coding RNA Biogenesisen_US
dc.subjectRNA Structureen_US
dc.subjectSpeciationen_US
dc.titleGenetic variation may play a crucial role in non-coding RNA biogenesisen_US
dc.typeArticleen_US
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