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Genetic variation may play a crucial role in non-coding RNA biogenesis
(Scientific Research Publishing, 2012-10)
Transcription, post-transcriptional modification, translation, post-translational modification, DNA replication, and signaling interaction of intra- and extra- cellular components are the relevant mechanisms in gene ...
Modulation of gastric mucosal inflammatory responses to Helicobacter pylori by ghrelin: Role of cNOS-dependent IKK-β S-nitrosylation in the regulation of COX-2 activation
(Scientific Research Publishing, 2012-04)
Disturbances in nitric oxide synthase (NOS) and cyclooxygenase (COX) isozyme systems, manifested by the excessive NO and prostaglandin (PGE2) generation, are well-recognized features of gastric mucosal inflammatory responses ...
Interaction of haptoglobin with hemoglobin octamers based on the mutation αAsn78Cys or βGly83Cys
(Scientific Research Publishing, 2012-01)
Octameric hemoglobins have been developed by the introduction of surface cysteines in either the alpha or beta chain. Originally designed as a blood substitute, we report here the structure and ligand binding function; in ...
A silkworm hemolymph protein is a prophenoloxidase activation blocker
(Scientific Research Publishing, 2012-10)
Melanization in insect hemolymph is triggered by the recognition of pathogen-associated molecular patterns via pattern recognition receptors. The signal transduction leads to the activation of the prophenoloxidase and hence ...
The full length PtSRP (Pisolithus tinctorius symbiosis related protein) fungal mRNA encodes a potential marker of ectomycorrhiza formation
(Scientific Research Publishing, 2012-07)
The Pisolithus tinctorius symbiosis related protein expressed sequence tag (EST PtSRP) was previously identified in the first hours of the interaction between the fungus Pisolithus tinctorius and sweet chestnut Castanea ...
The effects of astragalus polysaccharide on zebrafish cell apoptosis and senescence
(Scientific Research Publishing, 2012-04)
Astragalus polysaccharide (AP) is the extraction of astragalus, which is a plant used in traditional Chinese herb medicine and may increase an orgainism’s resistance to stress. Several earlier studies in vitro have indicated ...
Suppression of Sup35 amyloid fibril formation by group II chaperonin from Thermoplasma acidophilum
(Scientific Research Publishing, 2012-07)
The Group II chaperonin from Thermoplasma acidophilum was added to the in vitro amyloid fibrillation reaction of yeast Sup35NM protein to assess its effects. By measuring the formation of Sup35NM fibrils in real time using ...
Release of exosomes and microvesicles harbouring specific RNAs and glycosylphosphatidylinositol-anchored proteins from rat and human adipocytes is controlled by histone methylation
(Scientific Research Publishing, 2012-07)
The transfer of proteins and nucleic acids from donor to acceptor cells via small membrane vesicles has been implicated with (patho)physiological consequences. Previously the upregulation of esterification and downregulation ...
A simple and efficient seed-based approach to induce callus production from B73 maize genotype
(Scientific Research Publishing, 2012-10)
The wild type maize genotype, B73, is not amenable for callus production and an efficient protocol for B73 maize callus induction has never been reported up-to-date. Scientific efforts in producing B73 maize callus using ...
Molecular surveillance of dengue virus in Bahia State, Brazil
(Scientific Research Publishing, 2012-01)
Dengue is an important emerging viruses, posing a threat to one-third of the global human population. In 2002, the introduction of DENV-3 in the state of Bahia produced massive epidemic (about 35,000 cases detected) and ...