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Association of XbaI GLUT1 Polymorphism with Susceptibility to Type 2 Diabetes Mellitus and Diabetic Nephropathy
(Scientific Research Publishing, 2016-03)
Objectives: Diabetic nephropathy (DN) is one of the chronic microangiopathic complications of
type 2 diabetes (T2DM) and has become the most frequent cause of end-stage renal disease. The
XbaI polymorphism in the glucose ...
Identification and Quantification of Corn, Soybean and Cotton Genetically Modified by Real Time PCR
(Scientific Research Publishing, 2015-07)
In order to obtain a cheaper method for quantification of transgenic events in corn, soybeans and
cotton, primers for real time PCR have been developed and optimized, with fluorescent BRYT
Green system. The DNA was ...
Suppression of Sup35 amyloid fibril formation by group II chaperonin from Thermoplasma acidophilum
(Scientific Research Publishing, 2012-07)
The Group II chaperonin from Thermoplasma acidophilum was added to the in vitro amyloid fibrillation reaction of yeast Sup35NM protein to assess its effects. By measuring the formation of Sup35NM fibrils in real time using ...
Release of exosomes and microvesicles harbouring specific RNAs and glycosylphosphatidylinositol-anchored proteins from rat and human adipocytes is controlled by histone methylation
(Scientific Research Publishing, 2012-07)
The transfer of proteins and nucleic acids from donor to acceptor cells via small membrane vesicles has been implicated with (patho)physiological consequences. Previously the upregulation of esterification and downregulation ...
Interaction between the Wilms tumour factor-1 element in the promoter of Amh and a downstream enhancer is required for a strong expression of the gene in pre-pubertal sertoli cells
(Scientific Research Publishing, 2013-07)
Amh (anti-Müllerian hormone) is a single copy gene which is expressed strongly in Sertoli cells in the foetal testis and participates in the onset of sexual differentiation. Its promoter driving the expression of a reporter ...
A simple and efficient seed-based approach to induce callus production from B73 maize genotype
(Scientific Research Publishing, 2012-10)
The wild type maize genotype, B73, is not amenable for callus production and an efficient protocol for B73 maize callus induction has never been reported up-to-date. Scientific efforts in producing B73 maize callus using ...
Molecular characterization and species composition of anopheline vectors of malaria along an altitudinal gradient on the highlands of Mambilla Plateau Northeast, Nigeria
(African Journal of Biological Sciences, 2020-01-01)
Diversity of species arises majorly from speciation and this has serious epidemiological implications to disease transmission. The study aimed to determine the species of anopheline vectors of malaria present in five ...
Eco-Friendly Farming Practices and the intensity of their adoption in the agroecosystems of Embu County, Kenya
(African Journal of Biological Sciences, 2020-01-01)
This study was conducted among households of Embu County in Kenya to determine the socioeconomic factors that influenced adoption of Eco-Friendly Farming Practices (EFFPs). Earlier studies had indicated clearly that Embu ...
Comparative in vivo antiplasmodial activities of different extracts of Lawsonia inermis, Tithonia diversifolia and Nauclea latifolia against Plasmodium berghei
(African Journal of Biological Sciences, 2020-01-01)
Traditional herbal medicines are potentially rich sources of new drugs against malaria and other infectious diseases. However, phytochemicals extracted from a medicinal plant is strongly dependent on the nature of the ...
Phenylketonuria: Genes in phenylketonuria, diagnosis, and treatments
(African Journal of Biological Sciences, 2020-01-01)
Introduction: Phenylketonuria (PKU) is a rare autosomal-recessive disorder inherited in accordance with the law of segregation. Detection tools for people with PKU can include Sanger Sequencing (SS) and Next Generation ...