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Fine particulate matter induces vascular endothelial activation 4 via IL-6 dependent JAK1/STAT3 signaling pathway. Toxicol.
(2016-04)
Exposure to PM2.5 has been strongly linked to endothelial dysfunction. However, the underlying mechanism
of PM2.5 on the vascular endothelial function is poorly understood. This study examined the toxic
effect and ...
1H NMR-based metabolomics study on repeat dose toxicity of fine particulate matter in rats after intratracheal instillation
(Elsevier, 2017-07)
Systemic metabolic effects and toxicity mechanisms of ambient fine particulate matter (PM2.5) remain uncertain. In order to investigate the mechanisms in PM2.5 toxicity, we explored the endogenous metabolic changes and ...
Gene expression profiles and bioinformatics analysis of human umbilical vein endothelial cells exposed to PM2.5
(Elsevier, 2017-05)
Cardiovascular system is demonstrated the main target of PM2.5 and the objective of this study was to explore the toxic effect and molecular mechanisms caused by PM2.5 in primary human umbilical vein endothelial cells ...
Co-exposure to amorphous silica nanoparticles and benzo[a]pyrene at low level in human bronchial epithelial BEAS-2B cells
(SpringerLink, 2016-11)
Both ultrafine particles (UFP) and polycyclic aromatic hydrocarbons (PAHs) are widely present in the environment, thus increasing their chances of exposure to human in the daily life. However, the study on the combined ...
The Malaysian health care system: Ecology, plans, and reforms.
(2016-01)
Malaysia is on its way to achieving developed nation status in the next 4 years. Currently, Malaysia is on track for three Millennium Development Goals (MDG1, MDG4, and MDG7). The maternal mortality rate, infant mortality ...
Utilization of ANC and PNC Services in Nepal: A Multivariate Analysis Based on Nepal Demographic Health Survey 2001 and 2006.
(Science Publishing Group, 2015-10-12)
Background: Maternal Mortality is a public health problem in Nepal, which was highest in 1990 among the South
Asian countries. Associated factors of maternal mortality are various; among them maternal health services such ...
Experience and Perceptions on Preterm Births among Women Attending ANC Clinic at Kisumu County Hospital, Kenya.
(researchjournali, 2018-03)
Preterm birth is one of the main causes of neonatal death, and it is now the second leading cause of death after pneumonia in children under the age of five. Kenya is estimated to have 12.3% preterm births and 22 neonatal ...
Early Mobilization and Physical Activity Improve Stroke Recovery: A Cohort Study of Stroke Inpatients in Kisumu County Referral Hospitals, Kenya
(2016-01)
Early mobilization in acute stroke care is highly recommended in a range of developed countries policy; however, in developing countries like Kenya, lack of evidence seems to hinder formulation and implementation of policy ...
Fine particle matters induce DNA damage and G2/M cell cycle arrest in human bronchial epithelial BEAS-2B cells
(SpringerLink, 2017-11)
There is compelling evidence that exposure to particulate matter (PM) is linked to lung tumorigenesis. However, there is not enough experimental evidence to support the specific mechanisms of PM2.5-induced DNA damage and ...
Low-dose combined exposure of nanoparticles and heavy metal compared with PM2.5 in human myocardial AC16 cells
(Springer, 2017-12)
The co-exposure toxicity mechanism of ultrafine particles and pollutants on human cardiovascular system are still unclear. In this study, the combined effects of silica nanoparticles (SiNPs) and/or carbon black nanoparticles ...