Oxidized phospholipids modify plasminogen and apolipoprotein(a): Implications for vascular disease
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Date
2012-04
Journal Title
Journal ISSN
Volume Title
Publisher
Scientific Research Publishing
Abstract
Whereas the close structural homology between human plasminogen and apolipoprotein(a) has been known for a number of years only recent studies have revealed that both proteins carry linked oxidized phospholipids that may modify the function of these proteins. Future studies should provide a better understanding of oxidized phospholipid adducts and the role played by lipoprotein-associated phospholipase A2 for which cleavage specificity has been established when these modified lipids are in a free form.
Description
Keywords
Plasminogen, Apolipoprotein(a), Lipoprotein(a), Oxidized Phospholipids, Oxidized Phosphatidylcholines
Citation
American Journal of Molecular Biology, 2012, 2, 110-112