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dc.contributor.authorMayeku, Philip Wafula
dc.contributor.authorHassanali, Ahmed M.
dc.contributor.authorKiremire, Bernard T.
dc.contributor.authorOdalo, Josiah O.
dc.contributor.authorHertweck, Christian
dc.date.accessioned2016-09-26T12:17:59Z
dc.date.available2016-09-26T12:17:59Z
dc.date.issued2013
dc.identifier.citationAfrican Journal of Traditional, Complementary, and Alternative Medicines (2013) 10(5):341-344en_US
dc.identifier.urihttp://hdl.handle.net/123456789/934
dc.descriptionWe are grateful to the Germany Academic Exchange Program (DAAD) which provided research funds for this work. We are also thankful to the Hans Knoll Institute of Natural Product Chemistry & Infection Biology, Germany, for providing space, material and supervision for carrying out anti-bacterial assays.en_US
dc.description.abstractParts of the plant Thalictrum rhyncocarpum are used in herbal medicine in Kenya to treat various infections. The aim of this study was to evaluate in-vitro anti-bacteria activities and phytochemical profiles of solvent extracts of the leaves, stem bark and root of Thalictrum rhyncocarpum against Bacillus subtilis-6633, Staphylococcus aures-SG 511, Escherichia coli SG 458, Pseudomonus aeruginosa-K799/61 and Mycobacterium vaccae-10670. Anti-bacterial activity tests were carried out using disc diffusion assay and tube dilution technique, and phytochemical screening was carried out through Thin Layer Chromatography. The crude extracts showed antibacterial effects on M. vaccae, P. aeruginosa and B. subtilis. M. vaccae was most sensitive, particularly to the methanol root extract. Phytochemical screening of the extracts suggested the presence of glycosides and alkaloids in the stem bark and root extracts, and flavonoids and triterpenes in the leaf extracts. The study showed interesting levels of activities of solvent extracts of different parts of T. rhyncocarpum against some of the bacteria tested (M. vaccae, P. aeruginosa and B. subtilis). The results provide some scientific rationale for the traditional use of the plant in Kenya to treat different microbial infections.en_US
dc.description.sponsorshipGermany Academic Exchange Program (DAAD)en_US
dc.language.isoenen_US
dc.subjectThalictrum rhyncocarpumen_US
dc.subjectEthno-medicinal planten_US
dc.subjectAnti-microbial activitiesen_US
dc.subjectPhytochemical profileen_US
dc.titleAnti-Bacterialactivities And Phytochemical Screening Of Extracts Of Different Parts Of Thalictrum Rhynchocarpumen_US
dc.typeArticleen_US


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