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The ATPase activity of molecular chaperone HSP60 is inhibited by immunosuppressant mizoribine
(Scientific Research Publishing, 2012-04)
The molecular chaperone HSP60 is a chaperonin homolog of GroEL. We had previously shown that the immunosuppressant mizoribine is bound directly to HSP60 and inhibited its chaperone activity. However, the inhibitory mechanisms ...