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Functional reconstruction of bovine P450scc steroidogenic system in Escherichia coli
(Scientific Research Publishing, 2013-10)
Mammalian cytochrome P450scc enzyme system catalyzes the initial step in steroid hormone biosynthesis—cholesterol hydroxylation followed by cleavage of the side-chain to yield pregnenolone. This system consists of three ...
N–nitrosodiethylamine cytochrome P450 induction and cytotoxicity evaluation in primary cultures of rat hepatocytes
(Scientific Research Publishing, 2011-07)
The primary routes of potential human exposure to N-nitrosodiethylamine (NDEA) are ingestion, inhalation, and dermal contact. Air, diet and smoking contribute to potential human exposure at levels of a few µg of NDEA/day. ...