Browsing Biology and Biotechnology by Subject "Allosteric Transition"

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    • Interaction of haptoglobin with hemoglobin octamers based on the mutation αAsn78Cys or βGly83Cys 

      Brillet, Thomas; Marden, Michael C.; Yeh, Joanne I.; Shen, Tong-Jian; Ho, Nancy T.; Kettering, Regina; Du, Shoucheng; Vasseur, Corinne; Domingues-Hamdi, Elisa; Ho, Chien; Baudin-Creuza, Véronique (Scientific Research Publishing, 2012-01)
      Octameric hemoglobins have been developed by the introduction of surface cysteines in either the alpha or beta chain. Originally designed as a blood substitute, we report here the structure and ligand binding function; in ...