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Combined Effect of Silica Nanoparticles and Benzo[a]pyrene on Cell Cycle Arrest Induction and Apoptosis in Human Umbilical Vein Endothelial Cells
(MDPI, 2017-03)
Particulate matter (PM) such as ultrafine particulate matter (UFP) and the organic
compound pollutants such as polycyclic aromatic hydrocarbon (PAH) are widespread in the
environment. UFP and PAH are present in the air, ...
Cellular pathways involved in silica nanoparticles induced apoptosis: A systematic review of in vitro studies.
(Elsevier, 2017-12)
Silica nanoparticles (SiNPs) have been found to pass through biological barriers and get distributed in the human body. They induce cell apoptosis via various mechanisms in body organs. To understand these mechanisms, we ...
Genome-wide transcriptional analysis of cardiovascular-related genes and pathways induced by PM2. 5 in human myocardial cells.
(2017-04)
Air pollution has been a major environment-related health threat. Most of the studies on PM2.5 toxicity have verified on the cardiovascular system and endothelial cells. However, researches on PM2.5-induced myocardial-related ...
Telomere Length and Accelerated Biological Aging in the China Suboptimal Health Cohort: A Case-Control Study
(Mary Ann Liebert, Inc, 2017-06)
Suboptimal health status (SHS) has been linked to cardiovascular risk factors, psychosocial stress, and unhealthy
lifestyle. These factors also contribute to the shortening of telomere length (TL). A case–control study
was ...
1H NMR-based metabolomics study on repeat dose toxicity of fine particulate matter in rats after intratracheal instillation
(Elsevier, 2017-07)
Systemic metabolic effects and toxicity mechanisms of ambient fine particulate matter (PM2.5) remain uncertain. In order to investigate the mechanisms in PM2.5 toxicity, we explored the endogenous metabolic changes and ...
Gene expression profiles and bioinformatics analysis of human umbilical vein endothelial cells exposed to PM2.5
(Elsevier, 2017-05)
Cardiovascular system is demonstrated the main target of PM2.5 and the objective of this study was to explore the toxic effect and molecular mechanisms caused by PM2.5 in primary human umbilical vein endothelial cells ...
Fine particle matters induce DNA damage and G2/M cell cycle arrest in human bronchial epithelial BEAS-2B cells
(SpringerLink, 2017-11)
There is compelling evidence that exposure to particulate matter (PM) is linked to lung tumorigenesis. However, there is not enough experimental evidence to support the specific mechanisms of PM2.5-induced DNA damage and ...
Low-dose combined exposure of nanoparticles and heavy metal compared with PM2.5 in human myocardial AC16 cells
(Springer, 2017-12)
The co-exposure toxicity mechanism of ultrafine particles and pollutants on human cardiovascular system are still unclear. In this study, the combined effects of silica nanoparticles (SiNPs) and/or carbon black nanoparticles ...
Maternal Vulnerabilities and Disparities in Availability of Antenatal Care Content in Kenya: Analysis of KDHS 2008/9
(Science and Education Publishing, 2017-09)
Background: ANC provides the opportunity to detect and treat anomalies of pregnancy and access to preventive maternal and child healthcare. However, detailed information about the actual quality and content of ANC in ...
Comprehensive gene and microRNA expression profiling on cardiovascular system in zebrafish co exposured of SiNPs and MeHg
(Elsevier, 2017-12)
Air pollution has been shown to increase cardiovascular diseases. However, little attention has been paid to the combined effects of PM and air pollutants on the cardiovascular system. To explore this, a high-throughput ...