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The diagnostic value of haematuria and proteinuria in Schistosoma haematobium infection in Southern Nigeria.

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dc.contributor.author Nwaorgu, O.C.
dc.contributor.author Anigbo, E.U.
dc.date.accessioned 2015-07-14T15:07:19Z
dc.date.available 2015-07-14T15:07:19Z
dc.date.issued 1992
dc.identifier.citation J. Helminthol. vol. 66 pp:177-185. en_US
dc.identifier.uri http://journals.cambridge.org/action/displayAbstract?fromPage=online&aid=1723656
dc.identifier.uri http://hdl.handle.net/123456789/204
dc.description.abstract Haematuria and proteinuria as detected by chemical reagent strips correlated moderately (r=0·7) with prevalence and intensity of infection with Schistosoma haematobium in an area of Anambra State, Nigeria. Differences attributable to age and sex were also reflected in a similar pattern, all peaks occurring in the 5–14 year age group. The differences observed with varying levels of intensity and haematuria at both 10 and 50 erythrocytes/μl (p<0·001) and proteinuria at 0·3 g/dl (p<0·01) were statistically significant. At a proteinuria level of 1 g/dl, the observed differences were however not statistically significant (p>0·5). The percentage of specimens from children (1–14 years) positive for S. haematobium eggs and with at least traces of haematuria and proteinuria (63·4% and 95%, respectively) was higher than in adults (33·3% and 80·2%, respectively). All individuals with more than 50 eggs/10 ml of urine were correctly identified using both indices either separately or in combination. For egg counts of less than 50 egg/10 ml of urine, false diagnosis occurred in only 5% of all specimens examined. The sensitivity and specificity of haematuria and proteinuria at trace quantities was very high, hut haematuria had a higher predictive value for a positive test (PvPt) and was considered the overall better indicator. A combination of both indices did not significantly increase the PvPt. When trace haematuria and moderate proteinuria were combined, both the sensitivity, specificity and PvPt were all above 90%, giving the best overall values in all the combinations made. en_US
dc.language.iso en en_US
dc.subject Schistosoma haematobium en_US
dc.subject man en_US
dc.subject Nigeria en_US
dc.subject haematuria en_US
dc.subject proteinuria en_US
dc.subject diagnosis en_US
dc.subject Trematoda en_US
dc.title The diagnostic value of haematuria and proteinuria in Schistosoma haematobium infection in Southern Nigeria. en_US
dc.type Article en_US


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