|The global business environment is today faced with uncertainty and various complexities. Innovation, taking risk and ability to pioneer ideas has been proven to contribute immensely to the financial wellness and strategic value of big corporations as well as small and medium enterprises. In the quest to address the causation for intrapreneurial orientation in organisations, the study investigated five independent variables namely; management support, work discretion, rewarding intrapreneurial efforts, time availability and organizational boundaries against one dependent variable, intrapreneurial orientation. The study, therefore, sought to address the strategic determinants of intrapreneurial orientation at the Kenya Institute of Management. The main objective was be to establish the strategic determinants of intrapreneurial orientation at the Kenya institute of management. The study population comprised of employees with strategic roles at the Kenya Institute of Management. Census survey was used in the study, data was gathered from every member of the population. Primary data was collected through a structured questionnaire measured on a five point Likert scale. Out of the 108 questionnaires administered, there were 81responses, a response rate of 75%. A two-step of statistical analysis was applied; the first stage involved descriptive statistical analysis where Means and standard deviations were computed. The second stage involved inferential analysis which was performed to determine the relationship among the variables. The study conducted correlation analysis to test the strength of association between the research variables using Pearson’s Product Moment Correlation Coefficient (r) statistical tool to help arrive at conclusions. Confirming the researcher’s expectations, the study established that, intrapreneurial orientation is largely composed of three indicators. These are; proactiveness, innovation and risk taking, which are the most significant measures of intrapreneurial orientation. The study also established that the main strategic determinants of intrapreneurial orientation are; management support, rewarding intrapreneurial effort, work discretion, time availability and organizational boundaries. The findings were in agreement with previous study results. From the regression model, these five determinants contribute 61% of intrapreneurial orientation at the Kenya Institute of Management. In conclusion management support, work discretion, rewarding intrapreneurial efforts and time availability are the key determinants of intrapreneurial orientation in organizations.