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dc.contributor.authorVeliká, Beáta
dc.contributor.authorTomečková, Vladimíra
dc.contributor.authorFodor, Krisztina
dc.contributor.authorKron, Ivan
dc.contributor.authorPerjési, Pál
dc.date.accessioned2018-07-12T12:09:35Z
dc.date.available2018-07-12T12:09:35Z
dc.date.issued2015-01
dc.identifier.citationSpectral Analysis Reviews, 2015, 3, 1-8en_US
dc.identifier.issn2331-2106
dc.identifier.urihttp://dx.doi.org/10.4236/sar.2015.31001
dc.identifier.urihttp://hdl.handle.net/123456789/1859
dc.description.abstractUV-VIS spectroscopic investigations of interaction of bovine and human serum albumin with selected chalcones (1) and their cyclic chalcone analogues: (E)-2-(4’-X-benzylidene-1-tetralones (3), benzosuberones (4) with dimethylamino and methoxy substituents and (E)-2-(2’,4’-dimethoxybenzylidene)-1-indanone (2) were performed in polar respiration medium. Absorption maxima of the tested compounds were investigated in the presence of bovine and human serum albumin at the 0, 10, 30 and 60 minute timepoints of the interaction. The absorbance of all studied compounds in the presence of proteins decreased after one hour of the reaction. Molecule 4a showed the strongest and fastest kinet initial interaction with both albumins.en_US
dc.language.isoenen_US
dc.publisherScientific Researchen_US
dc.subjectChalconesen_US
dc.subjectCyclic Chalcone Analoguesen_US
dc.subjectUV Spectraen_US
dc.subjectKinetic Measurementsen_US
dc.subjectBinding Constant Bovine Serum Albuminen_US
dc.subjectHuman Serum Albuminen_US
dc.title(E)-2-Benzylidenecycloalkanones XII.* Kinetic Measurement of Bovine and Human Serum Albumine Interaction with Selected Chalcones and Their Cyclic Chalcone Analogues by UV Spectrophotometryen_US
dc.typeArticleen_US


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