Browsing by Subject "β-Lactam Antibiotics"

Now showing items 1-2 of 2

    • Identification and preliminary characterization of novel B3-type metallo-β-lactamases 

      Miraula, Manfredi; Brunton, Conor S.; Schenk, Gerhard; Mitić, Nataša (Scientific Research Publishing, 2013-10)
      Antibiotic resistance has emerged as a major global threat to human health. Among the strategies employed by pathogens to acquire resistance the use of metallo-β-lactamases (MBLs), a family of dinuclear metalloenzymes, is ...

    • Unusual metallo-β-lactamases may constitute a new subgroup in this family of enzymes 

      Hou, Chun-Feng D.; Phelan, Emer K.; Miraula, Manfredi; Ollis, David L.; Schenk, Gerhard; Mitić, Nataša (Scientific Research Publishing, 2014-01)
      Metallo-β-lactamases (MBLs) are a family of Zn2+-dependent enzymes that have contributed strongly to the emergence and spread of antibiotic resistance. Novel members as well as variants of existing members of this family ...