Now showing items 1-3 of 3

    • Identification and preliminary characterization of novel B3-type metallo-β-lactamases 

      Miraula, Manfredi; Brunton, Conor S.; Schenk, Gerhard; Mitić, Nataša (Scientific Research Publishing, 2013-10)
      Antibiotic resistance has emerged as a major global threat to human health. Among the strategies employed by pathogens to acquire resistance the use of metallo-β-lactamases (MBLs), a family of dinuclear metalloenzymes, is ...
    • Inteins—A Focus on the Biotechnological Applications of Splicing-Promoting Proteins 

      Miraula, Manfredi; Enculescu, Charmaine; Mitić, Natasa; Schenk, Gerhard (Scientific Research Publishing, 2015-03)
      The main aim of this mini-review is to illustrate strategies and industrial applications based on inteins (INTErnal proteINS), which belong to a class of autocatalytic enzymes that are able to perform a catalytic reaction ...
    • Unusual metallo-β-lactamases may constitute a new subgroup in this family of enzymes 

      Hou, Chun-Feng D.; Phelan, Emer K.; Miraula, Manfredi; Ollis, David L.; Schenk, Gerhard; Mitić, Nataša (Scientific Research Publishing, 2014-01)
      Metallo-β-lactamases (MBLs) are a family of Zn2+-dependent enzymes that have contributed strongly to the emergence and spread of antibiotic resistance. Novel members as well as variants of existing members of this family ...